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Professor
208C Brehm
2505 River Drive
Knoxville, TN 37996-4574
(865) 974-2887
Fax: (865) 974-7297
Email: asaxton@utk.edu
Research Appointment: 80%
Teaching Appointment: 20%
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DOWNLOADABLE COMPUTER SOFTWARE
Non-Linear Enzyme Kinetics
The NLINEK SAS macro analyzes various bi-substrate enzyme kinetic
data, including models with inhibition. The nonlinear mixed model
algorithm in SAS has been found to perform very well with complex
models.
Download nlinek.sas
Download Users
Guide
Download Example files:
Quad3_Kinetics.xls
R67_Folate_Inhibition.xls
R67_NADH_Kinetics.xls
R67_Q67H_Kinetics.xls
Proc Mixed Mean Separation Formatting
This macro formats pair-wise differences from SAS Proc MIXED,
created by the PDIFF option on the LSMEANS statement. The differences
are used to create groups of similar means, represented by letters
A, B, etc. Documentation is included as comments at the top of
the program file.CITATION: Saxton, A.M. 1998. A macro for converting
mean separation output to letter groupings in Proc Mixed. In Proc.
23rd SAS Users Group Intl., SAS Institute, Cary, NC, pp1243-1246.
Nashville, TN, March 22-25.
Download PDMIX800 For SAS Version
8 or higher (Updated 8/8/03)
Download PDMIX612 For SAS Version
6.12
Download PDGLM800 Equivalent functionality
for Proc GLM, Version 8 or higher.
Bi-Substrate Enzyme Kinetics
This SAS macro analyzes sub-saturating bi-substrate enzyme kinetic
data, in which one substrate is held constant and the other is
varied. Weighted regression is used to produce estimates of Km
and Vmax from inverse rate - inverse substrate plots. Usage is
described in comments at the top of the file. Citation: Smiley,
RD, Hicks, SN, Stinnett, LG, Howell, EE and Saxton, AM. 2002.
Bi-substrate kinetics using SAS computer software. Analytical
Biochemistry 301(1): 153-156.
Download BISUBEK
User Manual
User Manual Example Data
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