The University of Tennessee
Institute of Agriculture
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Assistant Professor
51A McCord Hall
2640 Morgan Circle Drive
Knoxville, TN 37996-4574
(865) 974-5598
Fax: (865) 947-7297
Email: jlin6@utk.edu

Research Appointment: 90%
Teaching Appointment: 10%

Focus Area:   

Infectious Diseases.

RECENT PUBLICATIONS

Refereed Papers

J. Lin, J.S. Hogan and K.L. Smith. 1998. In Vitro Growth Inhibition of Coliform Bacteria by Monoclonal Antibody Directed against Ferric Enterobactin Receptor FepA. J. Dairy Sci. 81:1267-1274.

J. Lin, J. S. Hogan, A. Mueen, and K. L. Smith. 1998. Immunization of Cows with Ferric Enterobactin Receptor FepA from Coliform Bacteria. J. Dairy Sci. 81:2151-2158.

J. Lin, J. S. Hogan, and K. L. Smith. 1999. Growth responses of Coliform Bacteria to Purified Bovine IgG Directed Against Ferric Enteobactin Receptor FepA. J. Dairy Sci. 82:86-92

J. Lin, J.S. Hogan, and K.L. Smith. 1999. Antigenic and Molecular Homology of the Ferric Citrate Receptor FecA of Coliform Bacteria Isolated from Naturally Occurring Bovine Intramammary Infections. Clinical and Diagnostic Laboratory Immunology 6(6):966-969.

J. Lin, S. Huang, and Q. Zhang. 2002. Bacterial outer membrane proteins: key players for adaptation in host niche. Microbes and Infections. 4:325-331

Takemura, K., J. S. Hogan, J. Lin, and K. L. Smith. 2002. Efficacy of Immunization with ferric citrate receptor FecA from Escherichia coli on induced coliform mastitis. J. Dairy Sci. 85:774-781.

J. Lin, L. Michel, and Q. Zhang. 2002. CmeABC functions as a multidrug efflux pump in Campylobacter jejuni. Antimicrob. Agents. Chemother. 46:2124-2131.

N. Luo. O. Sahin, J. Lin, L. O. Michel, and Q. Zhang. 2003. In vivo selection of Campylobacter isolates with high levels of fluoroquinolone resistance associated with gyrA mutations and the function of the CmeABC efflux pump. Antimicrob. Agents. Chemother. 47:390-394.

J. Lin, O. Sahin, L. Michel, and Q. Zhang. 2003. Critical role of multidrug efflux pump CmeABC in bile resistance and in vivo colonization of Campylobacter jejuni. Infec. Immun. 71:4250-4259.

Q. Zhang, J. Lin, and S. Pereira. 2003. Fluoroquinolone-resistant Campylobacter in animal reservoirs: dynamics of development, resistance mechanisms, and ecological fitness. Animal Health Research Reviews 4(2):63-71.

J. Lin, M. Akiba, O. Sahin, Q. Zhang. 2005. CmeR functions as a transcriptional repressor of the multidrug efflux pump CmeABC in Campylobacter jejuni. . Antimicrob. Agents. Chemother. 49:1067-1075.

N. Luo, S. Pereira, O. Sahin, J. Lin, S. Huang, L. Michel, and Q. Zhang. 2005. Enhanced in vivo fitness of fluoroquinolone-resistant Campylobacter jejuni in the absence of antibiotic selection pressure. P.N.A.S Proc. Natl. Acad. Sci. 102(3):541-546.

J. Lin, C. Cagliero, B. Guo, E. Barton, M.C. Maurel, S. Payot, and Q. Zhang. 2005. Bile salts modulate expression of multidrug efflux pump CmeABC in Campylobacter jejuni. J. Bacteriol. 187:7417-7424.

M. Akiba, J. Lin, E. Barton, and Q. Zhang. 2006. Interaction of CmeABC and CmeDEF in conferring antimicrobial resistance and maintaining cell viability in Campylobacter jejuni. J. Antimicb. Chemother. 57:52-60.

A. Martinez, and J. Lin. 2006. Effect of an efflux pump on the function of CmeABC efflux pump and antibiotic resistance in Campylobacter jejuni. Foodborne Pathogens and Disease 3: 393-402

J. Lin, and A. Martinez . 2006. Effect of efflux pump inhibitors on bile resistance and in vivo colonization of Campylobacter jejuni. J. Antimicb. Chemother 58:966-972

M. Yan, O. Sahin, J. Lin, and Q. Zhang. 2006. Role of the CmeABC efflux pump in the emergence of fluoroquinolone-resistant Campylobacter under selection pressure. J. Antimicb. Chemother 58:1154-1159

Book Chapters

J. Lin, M. Akiba, and Q. Zhang. 2004. Multidrug efflux systems in Campylobacter. Pp205-218 In M.E. Konkel (ed), Campylobacter:Molecular and Cellular Biology. Horizon Scientific Press, Wymondham, U.K..